This is the reference list from the book: The Evolution of Aging - How Darwin's Dilemma is Affecting Your Chance for a Longer and Healthier Life T. C. Goldsmith 2003. This short book describes traditional and new theories of aging and is available as a paperback (ISBN: 0595280692), as a downloadable (PDF) file, (free) or as an HTML document. A summary of the evolvability theory of aging and the research implications of various theories is also available at http://www.azinet.com/aging/.
These books are available from many publishers.
The Origin of Species - Charles Darwin, 1859
http://www.literature.org/authors/darwin-charles/the-origin-of-species/
The Descent of Man – Charles Darwin, 1871
http://www.literature.org/authors/darwin-charles/the-descent-of-man/
An Unsolved Problem of Biology Medawar, P.B., 1952. H.K. Lewis & Co., London. http://www.telomere.org/Downloads/Medawar-UPB.pdf Medawar’s paper developed the idea that individual members of a non-aging population would have progressively less impact on evolution with increasing calendar age and introduced the mutation accumulation theory of aging. See summary and critique here.
Pleiotropy, natural selection and the evolution of senescence, Williams, G. 1957. Evolution 11, 398-411 http://www.telomere.org/Downloads/Williams_searchable.pdf Williams’ antagonistic pleiotropy theory is one of the most respected of the traditional theories. See summary and critique here.
The evolution of ageing and longevity. T.B.L. Kirkwood & F.R.S. Holliday (1979). Proceedings of the Royal Society of London B 205: 531-546. The disposable soma theory. See summary and critique here.
Senescence.info - A collection of information and links on ageing, and gerontology by Joao Magalhaes at The University of Namur in Belgium http://www.senescence.info/
No Truth to the Fountain of Youth - Olshansky,
Hayflick, and Carnes, Scientific American June 2002 – This article
provides warnings against common ineffective anti-aging remedies.
Aging is an “inescapable biological reality”; caused by the
accumulation of random damage to the building blocks of life (Fifty-one
traditional scientists endorsed this position paper to the effect that aging is
not and cannot be an evolved characteristic or adaptation.) http://www.sciam.com/explorations/2002/051302aging/
Evolutionary Theories of Aging and Longevity - L. A. Gavrilov et al; University of Chicago Center on Aging -- Links to many articles by this team - Excellent overview of evolutionary theories of aging including Weismann (evolved) and mutation accumulation / antagonistic pleiotropy (non-evolved). Describes negative impact of some aging theories on research - Cautions that all aging theories are just theories and should not unduly influence research. http://www.src.uchicago.edu/~gavr1/
Aging is a Specific Biological Function Rather than the Result of a Disorder in Complex Living Systems: Biochemical Evidence in Support of Weismann's Hypothesis, V. P. Skulachev Moscow State University -- http://protein.bio.msu.su/biokhimiya/contents/v62/full/62111394.htm
Whence Cometh Death- J. Mitteldorf; University of Pennsylvania – This site contains a good discussion of group selection and the evolved vs non-evolved controversy as well as links to most of Mitteldorf’s articles http://mathforum.org/~josh/
Aging as an Evolved Characteristic – Weismann’s Theory Reconsidered T. C. Goldsmith 2002. Article discusses evolutionary disadvantages of immortality and suggests that aging is a necessary adaptation. http://www.azinet.com/aging/aging-theory3.pdf
Shattered: Medawar's Test Tubes and their Enduring Legacy of Chaos - J. Bowles , Quarterly Review of Biology 73:3-49. (2000) -- Presents extensive criticism of Medawar's 1952 paper which is the basis of traditional theories of aging.
Reversing the Negative Genomic Effects of Aging with Short-Term Calorie Restriction - S. Spindler, University of California; Scientific World October 12, 2001 -- see overview at http://www.lef.org/featured-articles/spindler_press_release01.html
The retardation of aging in mice by dietary
restriction: longevity, cancer, immunity and lifetime energy intake.
Weindruch R, Walford RL, Fligiel S, Guthrie D., J Nutrition 1986; 116:
641-54. One of many reports
documenting slowing of aging by means of caloric restriction.
Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Kimura KK, Tissenbaum HA, Liu Y, Ruvkun G. Science 1997; 277: 942. A report of the discovery of a gene controlling aging in the roundworm.
The Serious Search for an Anti-Aging Pill - M.
A. Lane, et al Scientific American Aug 2002, -- Describes experiments
with D2G to simulate the effect of Caloric Restriction.
Progeria Research Foundation http://www.progeriaresearch.org/
Werner's Syndrome Overview http://depts.washington.edu/statgen/Computing/wsbackgrnd.html
Information on Long-lived Animals with Negligible Senescence http://www.agelessanimals.org
Longevity Records: Life Spans of Mammals, Birds,
Amphibians, Reptiles, and Fish, Max Plank
Institute, ISBN 87-7838-539-3 -- The oldest lake sturgeon caught so far was 152
years old. http://www.demogr.mpg.de/?http://www.demogr.mpg.de/longevityrecords/
Confirmation on longevity in Sebastes diploproa (Pisces: Scorpaenidae) from 210Pb/226Ra measurements in otoliths. Bennett, J.T. et al. 1982. Maritime Biology. 71, 209-215. Describes measurements of age in caught specimens of Rockfish.
Information
on Bighorn Sheep: http://www.desertusa.com/big.html
DesertUSA.com
Genes VIII Benjamin Lewin, 2004 Oxford University Press ISBN: 019879276X 990pp. A very comprehensive college level textbook on genetics that has an associated subscription to online updates. ($130).
Human Genome Project. The HGP is an approximately $3 billion government effort to fully sequence the human genetic code and identify all of the genes in human DNA. The effort which began in 1990 was substantially completed in 2003. The second link is for online copies of the actual preliminary project reports dated 2001.
http://www.ornl.gov/TechResources/Human_Genome/
http://www.ornl.gov/TechResources/Human_Genome/project/journals/journals.html
Copyright 2004 T. Goldsmith